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ISEH Webinars

Upcoming Webinar:

2020 Spring Webinar: Engineered hematopoietic microenvironments

The bone marrow microenvironment contains cellular niches that maintain the pool of hematopoietic stem cells while supporting hematopoietic maturation. Furthermore, hematological malignancies co-opt normal cellular interactions in order to promote their own growth and evade therapy. In vivo systems to study human hematopoiesis have mostly been achieved through xenotransplantation into immunodeficient mouse models. However, incomplete cross-compatibility between the murine stroma and transplanted human hematopoietic cells limit the rate of engraftment and the study of relevant interactions. Recently, several groups have reported as an alternative strategy the use of three-dimensional human bone marrow organoids in vivo and in vitro, generated from bone marrow stromal cells seeded onto osteoinductive scaffolds. In this ISEH New Investigator webinar, we will hear from two experts in this field: Dr. Dominique Bonnet from the Francis Crick Institute and Dr. Paul Bourgine from Lund University. We hope you can join us!


Live Webinar: Thursday 16 April at 9:00 am US CT (check your time zone here)

Presented by

Prof Dominique Bonnet, PhD, Francis Crick Institute, London

Paul Bourgine, PhD, Lund University


Moderated by

Francois Mercier, MD, McGill University 



Members: Click here to register

Non-Members: Pay your non-member registration fee then click here to register


The ISEH Webinar Series is FREE for ISEH members ($75 annual value). Cost for non-members is $25 per webinar. Want to become a member? Click here


Most Recent Webinar (Recording Available):

2019 Fall Webinar: Tracing single cell fates in hematopoiesis: Follow up from the 2019 NI Tech Session

The coordinated differentiation of hematopoietic stem and progenitor cells into the various mature blood cell types is responsible for sustaining blood and immune system homeostasis. The cell fate decisions underlying this important biological process are made at the level of single cells. Methods to trace the fate of single cells are therefore essential to understanding the hematopoietic system activity in health and disease. In this ISEH New Investigator webinar, we will hear from three technical experts about some of the most powerful methods available to trace cell fate in the hematopoietic system; Joana Carrelha from the University of Oxford, Dawn Lin from the Walter and Eliza Hall Institute of Medical Research, and Alejo Rodriguez-Fraticelli from Harvard University, with moderation by Simon Haas from Heidelberg Institute for Stem Cell Technology and Experimental Medicine. This webinar will cover the basic methodologies and technical considerations for single cell transplantation assays, lentiviral barcoding technologies, and sleeping beauty barcoding.

Presented by

Joana Carrelha, DPhil, MRC Weatherall Institute of Molecular Medicine, University of Oxford

Dawn Lin, PhD, Walter and Eliza Hall Institute of Medical Research

Alejo Rodriguez-Fraticelli, PhD, Harvard University and Boston Children’s Hospital


Moderated by

Simon Haas, PhD, German Cancer Research Center (DKFZ) & Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM)


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