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April 2010 Issue

Connections in Hematology & Stem Cells is supported by a grant from 

In the April 2010 issue
From the President’s Desk | Society News – award nominations, membership renewal
Annual Scientific Meeting Update – abstract submission, registration, young investigator events, committees | Member Profiles – Toshio Suda, David Scadden

From the President's Desk...

As we find ourselves in the midst of a quick-paced, mobile culture, the need for a means to share information in an easy-to-access, digestible format has become evident.

To address this need, I am very pleased to introduce Connections in Hematology & Stem Cells.

This new quarterly electronic newsletter will not only provide you with Society and Annual Scientific Meeting news and updates, but it will serve to facilitate the sharing of information about people, events, and initiatives in the field of experimental hematology around the world. The goal is for each issue to be timely, inclusive, and, of course, interesting.

We welcome your input and thoughts, as well as your contributions. As a member of ISEH, this communication tool is designed to meet your informational needs, so we can't stress enough that your feedback will be key to the success of Connections in Hematology & Stem Cells. If you are interested in contributing content or feedback, please do so by dropping a quick note to us at We look forward to hearing from you.


Toshio Suda, MD
Keio University School of Medicine
ISEH - Society for Hematology and Stem Cells President

Society News...

Celebrate Your Colleagues’ Success
ISEH Awards Nominations Deadline: 29 April

ISEH is now accepting nominations for the following two meritorious awards, which acknowledge those dedicated to the advancement of hematology and stem cell scientific research.

The Metcalf Award honors Professor Donald Metcalf, whose pioneering research revealed the control of blood cell formation and the role of hematopoietic cytokines. In the 1960s he developed techniques to culture blood cells, which led to the discovery of colony-stimulating factors (CSFs), which are responsible for resistance to infection. This award, given in his honor, recognizes distinguished scientists in the field of hematology and stem cell biology.

The McCulloch and Till Award honors Professors Ernest McCulloch and James Till, who, together, created the first quantitative, clonal method to identify stem cells and used this technique for pioneering studies on stem cells. McCulloch’s experience in hematology combined with Till's experience in biophysics yielded a novel and productive combination of skills and interests. This award, given in their honor, recognizes junior scientists in the field of hematology and stem cell biology.

Nominees for either of these two awards must be current ISEH members and be available to give a featured lecture at the 2010 ISEH 39th Annual Scientific Meeting this September in Melbourne, Australia. Board and committee members may not be nominated.

In addition to being invited to speak at this year’s meeting, each recipient will receive a complimentary registration to the conference, up to five hotel nights, a travel allowance, and a $1,000 honorarium.

This is a great opportunity to recognize a deserving colleague for their recent successes and contributions to the field.

Ensure Your Membership Is Current, or Join ISEH

For more than 60 years, the Society for Hematology and Stem Cells (ISEH) has been the premier forum for scientists worldwide to present and discuss leading-edge science in experimental hematology. For those not already aware, the ISEH Scientific Meeting was the chosen venue at which Dr. E. Donnall Thomas initially presented his work leading to his 1990 Nobel Prize in Medicine. ISEH membership positions you at the heart of the science and next to the most prestigious leaders in the field.

In addition to the unparalleled professional connections you experience as a member in the Society, benefits of membership include:

  • Full members receive a personal subscription and exclusive full-text online access to the journal, Experimental Hematology, including supplements and abstracts for ISEH-supported meetings*;
  • Qualified students and PhD fellows benefit from meetings that are focused on the success of young investigators by making it easier for them to publish quality science and meet senior researchers in smaller, more accessible meeting venues;
  • Leading scientists have an opportunity to meet young investigators and help them develop their career and research opportunities around the world;
  • Members benefit from reduced registration fees at the ISEH Annual Scientific Meeting and other selected educational events organized or supported by ISEH;
  • Members are eligible for prestigious ISEH awards and travel grants**;
  • Members are eligible to vote and have the opportunity to serve on ISEH Committees and Board of Directors***;
  • Members have exclusive access to the Members Area of the ISEH web site,, which includes, but is not limited to, a Membership Directory and access to upload affiliated meeting announcements for inclusion in the ISEH Calendar of Events.

* Students and PhD fellows who wish to receive the subscription must elect to become Full Members
** Each award or grant may have its own specific requirements
*** Voting and committee opportunities open to Full Members and Associate Members

For the advancement of their careers and science, young investigators in particular should ensure that they remain a member of this truly exclusive international hematology and stem cell society, where the quality of science and the international dimension are of primary importance. If you have any questions regarding your membership status, contact us at If your 2010 membership is outstanding, renew today.

Annual Scientific Meeting Update…

Share Your Science

Gain the recognition you deserve by submitting an abstract to the 39th Annual Scientific Meeting of the Society for Hematology and Stem Cells (ISEH). Abstract submission is open through 3 May 2010.

ISEH is specifically seeking research in the areas of:

  • ES/iPS derived blood cells
  • HSC microenvironment/mobilisation/homing/vascular biology
  • HSC biology/ differentiation
  • Transplantation and drug development
  • Leukemia/lymphoma
  • Developmental biology
  • MicroRNAs in hemopoiesis

If your abstract is accepted, and you are a student or PhD fellow, you may also be eligible for a travel grant up to AUD$2000 depending on the point of origin from which you are traveling. Travel grants will be awarded again this year as a component of the scientific abstract review and will be considered on the basis of scientific merit. Travel grant requests must be submitted no later than 3 May to be considered.

Registration Now Open

Registration is now open for ISEH 2010, 15-18 September, at the Melbourne Convention & Exhibition Centre in Melbourne, Australia.

Members who register before 1 June will save AUD$150.

This exclusive, scientific meeting is the annual forum for the exchange and discussion of original, unpublished, and significant research advances in the area of hematology and stem cell biology.

This year's program presents 28 sessions over 3 1/2 days, including: the Metcalf Award Lecture, the Till and McCulloch Award Lecture, the Presidential Symposium; Stem Cell Niche Interactions, and scientifically intriguing plenary, oral, and poster sessions.

"As chairman of the Local Organizing Committee, I am absolutely thrilled to be hosting my distinguished colleagues from all over the world, here in Melbourne," commented Susie Nilsson, PhD, Commonwealth Science and Industrial Research Organization (CSIRO). "The Scientific Program Committee has put together an exciting program; there are great networking events for new investigators and students and many travel grants to offer."

ISEH especially encourages and rewards excellence and innovation in experimental hematology by young investigators entering the field. The meeting is a unique and essential international gathering at which promising young investigators from around the world come together to meet with, learn from, and present their findings to prominent figures and leading researchers in the field. Additionally, special programs and activities are planned this year for the young investigator community. (See below for "Young Investigator Events Down Under.")

Plus, ISEH has negotiated special rates at the Hilton Melbourne/South Wharf, Crown Promenade/Crown Metropol, and the Crown Plaza Melbourne. To obtain the discounted ISEH 2010 meeting room rate you need to book your hotel by 1 June.

For your convenience, you can register for the conference and book your hotel on line at

Young Investigator Events Down Under

If you are a young investigator who is planning to attend the ISEH 2010 Annual Scientific Meeting in Melbourne this fall, then you won't want to miss out on the special young investigator events that have been planned with your networking needs in mind.

These events provide a forum for young investigators to meet established professors from around the world who are experts in  many aspects of stem cell biology and hematopoiesis, discuss career paths with senior scientists from academia and industry, and socialize with other young investigators who will be their colleagues for years to come. These events include:

  • Meet-the-Professor Breakfast;
  • Young Investigator Night Out;
  • Career Panel Discussion: Academia, Industry, and Translational Research

To participate in these young investigator events, you can add the young investigators package for only AUD$75 to your meeting registration. Specific details on participating professors and logistics are posted on

Special Thanks

ISEH would like to thank the members of the ISEH 2010 Meeting Scientific Organizing Committee and Local Organizing Committee for their time and personal contributions to the organization through this service.

Scientific Organizing Committee

Toshio Suda, MD
Keio University School of Medicine

David Scadden, MD
Massachusetts General Hospital Harvard

Toshio Kitamura, MD, PhD
University of Tokyo Institute of Medical Sciences

David Haylock, PhD
Commonwealth Science and Industrial Research Organization

Susie Nilsson, PhD
Commonwealth Science and Industrial Research Organization

Local Organizing Committee

Susie Nilsson, PhD
Commonwealth Science and Industrial Research Organization

David Haylock, PhD
Commonwealth Science and Industrial Research Organization<

Ivan Bertoncello, PhD
Australian Stem Cell Centre

Andrew Roberts, MBBS, PhD
Walter and Eliza Hall Institute

Toshio Kitamura, MD, PhD
University of Tokyo Institute of Medical Sciences

Ngaire Elwood, PhD
BMDI Cord Blood Bank & Murdoch Children's Research Institute

Andrew Elefanty, MBBS, PhD, FRACP
Monash Immunology and Stem Cell Institute

David Curtis, MBBS, PhD, FRACP, FRCPA
Royal Melbourne Hospital

Member Profiles...

ISEH, comprised of industry leaders in hematology, immunology, stem cell research, and cell and gene therapy, connects members worldwide for the opportunity to advance scientific knowledge. Each issue of Connections in Hematology & Stem Cells will introduce you to a few of those members. This issue, meet Toshio Suda and David Scadden.

Toshio Suda, MD
ISEH President

Dr. Toshio Suda is professor of developmental biology in the Sakaguchi laboratory in the School of Medicine at Keio University. He became enchanted by the secrets of hematopoiesis when studying in Dr. Makio Ogawa's lab at the Medical University of South Carolina in Charleston and chose his life's work. The two proposed a stochastic model in the differentiation of stem cells, a classical work showing the independent differentiation of stem cells from growth factors.

Dr. Suda identified the niche for hematopoietic stem cells and subsequently established the new field of oxidative stress and stem cell aging. The interaction of stem cells and niches is one of the hot topics in stem cell biology today.

In addition to his efforts at Keio Univeristy, Dr. Suda serves the field through professional societies and publications, such as his role as ISEH president and Scientific Program Committee member, and member of the International Society of Stem Cell Research. He sits on the editorial boards of several publications including Blood (American Society for Hematology), Journal of Experimental Medicine, Cell Stem Cell, and Stem Cells. He is editor-in-chief of the International Journal of Hematology (Japanese Society of Hematology).

Dr. Suda values his ISEH participation. "ISEH is a rather small international meeting where we can focus on in-depth discussion of timely topics. I appreciate the friendly atmosphere and look forward to reuniting with professional friends. At the Melbourne meeting, I am excited to once again see Dr. D. Metcalf, whose work on hemopoietic colonies taught me many things early in my career."

When not involved in his scientific pursuits, Dr. Suda is quite interested in history and would like to furthur understand ancient script and literature.

David Scadden, MD

Dr. David Scadden is the Gerald and Darlene Jordan Professor of Medicine at Harvard University. He and Professor Douglas Melton founded and jointly direct the Harvard Stem Cell Institute which is the largest institute dedicated to bringing stem cell biology to medical care in the world. With Professor Melton, Professor Scadden founded and co-chairs the Department of Stem Cell and Regenerative Biology at Harvard University, the first department to span faculties in Harvard's 371-year history.

He is a hematologist/oncologist and directs the Center for Regenerative Medicine at the Massachusetts General Hospital (MGH) while also chairing the hematologic malignancies program in the MGH Cancer Center.

He is an expert on the medical applications of stem cell biology with a particular emphasis on their use in the settings of cancer and AIDS. He has published more than 250 scientific papers and book chapters, and his laboratory has made fundamental contributions regarding how the stem cell niche regulates stem cell function, in defining the molecules limiting stem cell growth, and in discovering a molecular basis for stem cell aging.

Dr. Scadden is the recipient of numerous honors including membership in the Institute of Medicine of the National Academies of Science and awards from the Doris Duke Charitable Trust, the Ellison Medical Foundation, the Burroughs Wellcome Fund, and the Leukemia and Lymphoma Society.

He has served or serves on the Board of Scientific Counselors for the National Cancer Institute, the Board of External Experts for the National Heart, Lung, and Blood Institute, Board of Directors of the International Society for Stem Cell Research, and ISEH. He is an associate member of the Broad Institute of Harvard and MIT. He serves on multiple editorial boards and scientific advisory boards and is a scientific founder of Fate Therapeutics, a private biotechnology company.

Do you want to know more? Drs. Suda and Scadden will be part of the Meet-the-Professors Breakfast Thursday, September 16, from 7-8 a.m. at the 2010 ISEH meeting in Melbourne.

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ISEH 47th Annual Meeting - Los Angeles, CA

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