April

 

November Tessa Laurie Holyoake, (March 17, 1963 – August 30, 2017): Remembering a life that knew no boundaries Connie J. Eaves   The microenvironment in myelodysplastic syndromes: Niche-mediated disease initiation and progression Allison J. Li, Laura M. Calvin   Comprehensive discovery of noncoding RNAs in acute myeloid leukemia cell transcriptomes Jin Zhang, Malachi Griffith, Christopher A. Miller, Obi L. Griffith, David H. Spencer, Jason R. Walker, Vincent Magrini, Sean D. McGrath, Amy Ly, Nichole M. Helton, Maria Trissal, Daniel C. Link, Ha X. Dang, David E. Larson, Shashikant Kulkarni, Matthew G. Cordes, Catrina C. Fronick, Robert S. Fulton, Jeffery M. Klco, Elaine R. Mardis, Timothy J. Ley, Richard K. Wilson, Christopher A. Maher   Signaling via Smad2 and Smad3 is dispensable for adult murine hematopoietic stem cell function in vivo Matilda Billing, Emma Rörby, Maria Dahl, Ulrika Blank, Silja Andradottír, Mats Ehinger, Stefan Karlsson   Septin 6 regulates engraftment and lymphoid differentiation potential of murine long-term hematopoietic stem cells Katharina Senger, Gina Marka, Karin Soller, Vadim Sakk, Maria Carolina Florian, Hartmut Geiger   Tet2 restrains inflammatory gene expression in macrophages Alyssa H. Cull, Brooke Snetsinger, Rena Buckstein, Richard A. Wells, Michael J. Rauh   Genetic risk of prediabetes and diabetes development in chronic myeloid leukemia patients treated with nilotinib Bruno Martino, Corrado Mammì, Claudia Labate, Silvia Rodi, Domenica Ielo, Manuela Priolo, Maurizio Postorino, Giovanni Tripepi, Francesca Ronco, Carmelo Laganà, Caterina Musolino, Marianna Greco, Giorgio La Nasa, Giovanni Caocci   The oligodendrocyte lineage transcription factor 2 (OLIG2) is epigenetically regulated in acute myeloid leukemia Arzu Yalcin, Marlon Kovarbasic, Julius Wehrle, Rainer Claus, Heiko Becker, Mahmoud Abdelkarim, Verena I. Gaidzik, Andrea Schmidts, Ralph Wäsch, Heike L. Pahl, Konstanze Döhner, Lars Bullinger, Justus Duyster, Michael Lübbert, Björn Hackanson

December

The slippery slope of hematopoietic stem cell aging Martin Wahlestedt, David Bryder   MicroRNA-22 controls interferon alpha production and erythroid maturation in response to infectious stress in mice Claudine S. Kadmon, Cameron T. Landers, Haiyan S. Li, Stephanie S. Watowich, Antony Rodriguez, Katherine Y. King   Thermal injury of the skin induces G-CSF-dependent attenuation of EPO-mediated STAT signaling and erythroid differentiation arrest in mice John G. Noel, Benjamin J. Ramser, Jose A. Cancelas, Francis X. McCormack, Jason C. Gardner   Effects of in vivo deletion of GATA2 in bone marrow stromal cells Shin Hasegawa, Tohru Fujiwara, Yoko Okitsu, Hiroki Kato, Yuki Sato, Noriko Fukuhara, Yasushi Onishi, Ritsuko Shimizu, Masayuki Yamamoto, Hideo Harigae   Lenalidomide modulates gene expression in human ABC-DLBCL cells by regulating IKAROS interaction with an intronic control region of SPIB Lauren A. Solomon, Carolina R. Batista, Rodney P. DeKoter   Identification of novel biomarkers for MLL-translocated acute myeloid leukemia Karine Lagacé, Fréderic Barabé, Josée Hébert, Sonia Cellot, Brian T. Wilhelm   PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo Terence A. McGonigle, Amy R. Dwyer, Eloise L. Greenland, Naomi M. Scott, Kevin N. Keane, Philip Newsholme, Helen S. Goodridge, Leonard I. Zon, Fiona J. Pixley, Prue H. Hart

May

Chromatin priming of genes in development: Concepts, mechanisms and consequences
Constanze Bonifer, Peter N. Cockerill

Induced pluripotent stem cell technology: A window for studying the pathogenesis of acquired aplastic anemia and possible applications
Mahmoud I. Elbadry, J. Luis Espinoza, Shinji Nakao

Hemangioblast, hemogenic endothelium, and primitive versus definitive hematopoiesis
Georges Lacaud, Valerie Kouskoff

Predictive value of pretransplantation molecular minimal residual disease assessment by WT1 gene expression in FLT3-positive acute myeloid leukemia
Anna Candoni, Federico De Marchi, Francesca Zanini, Maria Elena Zannier, Erica Simeone, Eleonora Toffoletti, Alexsia Chiarvesio, Michela Cerno, Carla Filì, Francesca Patriarca, Renato Fanin

Androgen receptor expression in mantle cell lymphoma: Potential novel therapeutic implications
Elahe A. Mostaghel, Paul S. Martin, Stephen Mongovin, Shani Frayo, Ailin Zhang, Kerstin L. Edlefsen, Oliver W. Press, Ajay K. Gopal

Use of ubiquitous, highly heterozygous copy number variants and digital droplet polymerase chain reaction to monitor chimerism after allogeneic haematopoietic stem cell transplantation
John B. Whitlam, Ling Ling, Michael Swain, Tom Harrington, Oksana Mirochnik, Ian Brooks, Sara Cronin, Jackie Challis, Vida Petrovic, Damien L. Bruno, Francoise Mechinaud, Rachel Conyers, Howard Slater

Governing roles for Trib3 pseudokinase during stress erythropoiesis
Arvind Dev, Ruth Asch, Edward Jachimowicz, Nicole Rainville, Ashley Johnson, Emily Greenfest-Allen, Don M. Wojchowski

Impact of TET2 deficiency on iron metabolism in erythroblasts
Kyoko Inokura, Tohru Fujiwara, Kei Saito, Tatsuya Iino, Shunsuke Hatta, Yoko Okitsu, Noriko Fukuhara, Yasushi Onishi, Kenichi Ishizawa, Kazuya Shimoda, Hideo Harigae

Shipping mouse bone marrow: Keep it in the bone
Ani E. Papazian, Youmna S. Kfoury, David T. Scadden

 

 

June

Application of vitamin D and vitamin D analogs in acute myelogenous leukemia
Huynh Cao, Yi Xu, Rosalia de Necochea-Campion, David J. Baylink, Kimberly J. Payne, Xiaolei Tang, Christina Ratanatharathorn, Yong Ji, Saied Mirshahidi, Chien-Shing Chen

Role of mTORC1–S6K1 signaling pathway in regulation of hematopoietic stem cell and acute myeloid leukemia
Joydeep Ghosh, Reuben Kapur

The evolving view of the hematopoietic stem cell niche
Isabel Beerman, Tiago C. Luis, Sofie Singbrant, Cristina Lo Celso, Simon Méndez-Ferrer

A defined role for multiple Fanconi anemia gene products in DNA-damage-associated ubiquitination
Winnie Tan, Andrew J. Deans

Rat acute GvHD is Th1 driven and characterized by predominant donor CD4+ T-cell infiltration of skin and gut
Margherita Boieri, Pranali Shah, Dasaradha Jalapothu, Olena Zaitseva, Lutz Walter, Bent Rolstad, Christian Naper, Ralf Dressel, Marit Inngjerdingen

Pharmacological inhibition of LSD1 and mTOR reduces mitochondrial retention and associated ROS levels in the red blood cells of sickle cell disease
Ramasamy Jagadeeswaran, Benjamin A. Vazquez, Muthusamy Thiruppathi, Balaji B. Ganesh, Vinzon Ibanez, Shuaiying Cui, James D. Engel, Alan M. Diamond, Robert E. Molokie, Joseph DeSimone, Donald Lavelle, Angela Rivers

The Calreticulin control of human stress erythropoiesis is impaired by JAK2V617F in polycythemia vera
Mario Falchi, Lilian Varricchio, Fabrizio Martelli, Manuela Marra, Orietta Picconi, Agostino Tafuri, Gabriella Girelli, Vladimir N. Uversky, Anna Rita Migliaccio

Novel roles for podocalyxin in regulating stress myelopoiesis, Rap1a, and neutrophil migration
Pan Li, Aldona A. Karaczyn, Rose McGlauflin, Amanda J. Favreau-Lessard, Edward Jachimowicz, Calvin P. Vary, Kailin Xu, Don M. Wojchowski, Pradeep Sathyanarayana

Targeted deletion of the Hoxa cluster affects B lymphopoiesis through depletion of early lymphoid progenitors
Charles-Étienne Lebert-Ghali, Alexander Thompson, Heather J. Melichar, Janet J. Bijl

 

January

 

Using zebrafish models of leukemia to streamline drug screening and discovery
Adam P. Deveau, Victoria L. Bentley, Jason N. Berman

Novel strategies of adoptive immunotherapy: How natural killer cells may change the treatment of elderly patients with acute myeloblastic leukemia
Roberto M. Lemoli, Sarah Parisi, Antonio Curti

Tumor necrosis factor α in the onset and progression of leukemia
Xiaoxi Zhou, Zhuoya Li, Jianfeng Zhou

Clinical-grade regulatory T cells: Comparative analysis of large-scale expansion conditions
Sarvari Velaga, Christina Alter, Ulrike Dringenberg, Christina T. Thiesler, Sandra Kuhs, Sven Olek, Sya N. Ukena, Anke Franzke

AC220 and AraC cause differential inhibitory dynamics in patient-derived M5-AML with FLT3-ITD and, thus, ultimately distinct therapeutic outcomes
Xiaoyu An, Jinping Liu, Na Wang, Di Wang, Liang Huang, Likun Zhang, Jie Cai, Jean-Pierre Wery, Demin Zhou, Jianfeng Zhou, Qi-Xiang Li

Constitutive Kit activity triggers B-cell acute lymphoblastic leukemia-like disease in mice
Robin R. Weidemann, Rayk Behrendt, Kristina B. Schoedel, Werner Müller, Axel Roers, Alexander Gerbaulet

Alterations in the bone marrow microenvironment may elicit defective hematopoiesis: a comparison of aplastic anemia, chronic myeloid leukemia, and normal bone marrow
Meerim Park, Chan-Jeoung Park, Young Wook Cho, Seongsoo Jang, Jung-Hee Lee, Je-Hwan Lee, Kyoo-Hyung Lee, Young Ho Lee

The AMP-activated protein kinase beta 1 subunit modulates erythrocyte integrity
Emma L. Cambridge, Zoe McIntyre, Simon Clare, Mark J. Arends, David Goulding, Christopher Isherwood, Susana S. Caetano, Carmen Ballesteros Reviriego, Agnieszka Swiatkowska, Leanne Kane, Katherine Harcourt, The Sanger Mouse Genetics Project, David J. Adams, Jacqueline K. White, Anneliese O. Speak

Sustained enhancement of OCTN1 transporter expression in association with hydroxyurea induced γ-globin expression in erythroid progenitors
Aisha L. Walker, Solomon F. Ofori-Acquah

Pharmacological inhibition of AKT activity in human CD34+ cells enhances their ability to engraft immunodeficient mice
Sisi Chen, Rui Gao, Michihiro Kobayashi, Hao Yu, Chonghua Yao, Reuben Kapur, Mervin C. Yoder, Yan Liu

Proinflammatory signals are insufficient to drive definitive hematopoietic specification of human HSCs in vitro
Alessandra Giorgetti, Julio Castaño, Clara Bueno, Rafael Díaz de la Guardia, Mario Delgado, Anna Bigas, Lluis Espinosa, Pablo Menendez

 

February

Ikaros: Exploiting and targeting the hematopoietic stem cell niche in B-progenitor acute lymphoblastic leukemia
Michelle L. Churchman, Charles G. Mullighan

Granulocyte colony-stimulating factor receptor signaling in severe congenital neutropenia, chronic neutrophilic leukemia, and related malignancies
Pankaj Dwivedi, Kenneth D. Greis

Transcriptional activation by MLL fusion proteins in leukemogenesis
Akihiko Yokoyama

Dynamic variation of CD5 surface expression levels within individual chronic lymphocytic leukemia clones
Rachael J.M. Bashford-Rogers, Anne L. Palser, Clare Hodkinson, Joanna Baxter, George A. Follows, George S. Vassiliou, Paul Kellam

Genetically re-engineered K562 cells significantly expand and functionally activate cord blood natural killer cells: Potential for adoptive cellular immunotherapy
Janet Ayello, Jessica Hochberg, Allyson Flower, Yaya Chu, Laxmi V. Baxi, William Quish, Carmella van de Ven, Mitchell S. Cairo

Lenalidomide enhances the function of dendritic cells generated from patients with multiple myeloma
Manh-Cuong Vo, Truc Anh-NguyenThi, Hyun-Ju Lee, Thanh-Nhan Nguyen-Pham, Thangaraj Jaya Lakshmi, Sung-Hoon Jung, Hyeoung-Joon Kim, Je-Jung Lee

MiR-17-92 represses PTPROt and PP2A phosphatases and amplifies tonic BCR signaling in DLBCL cells
Ewa Jablonska, Patryk Gorniak, Maciej Szydlowski, Tomasz Sewastianik, Emilia Bialopiotrowicz, Anna Polak, Krzysztof Warzocha, Przemyslaw Juszczynski

AML1–ETO promotes SIRT1 expression to enhance leukemogenesis of t(8;21) acute myeloid leukemia
Lei Zhou, Qian Wang, Xiaosu Chen, Lin Fu, Xiaodong Zhang, Lijun Wang, Ailing Deng, Dandan Li, Jing Liu, Na Lv, Lili Wang, Yonghui Li, Daihong Liu, Li Yu, Liping Dou

Csk-binding protein controls red blood cell development via regulation of Lyn tyrosine kinase activity
Janice H.C. Plani-Lam, Neli S. Slavova-Azmanova, Nicole Kucera, Alison Louw, Jiulia Satiaputra, Peter Singer, Kong-Peng Lam, Margaret L. Hibbs, Evan Ingley

HIF1α-induced PDGFRβ signaling promotes developmental HSC production via IL-6 activation
Sung-Eun Lim, Virginie Esain, Wanda Kwan, Lindsay N. Theodore, Mauricio Cortes, Isaura M. Frost, Sarah Y. Liu, Trista E. North

Erratum to “Effect of roflumilast, novel phosphodiesterase-4 inhibitor, on lung chronic graft-versus-host disease in mice”
Sei Won Kim, Ji Young Lim, Chin Kook Rhee, Ji Hye Kim, Chan Kwon Park, Tae Jung Kim, Chul Soo Cho, Chang Ki Min, Hyoung Kyu Yoon

Erratum to “Autophagy regulates the cell cycle of mouse HSPCs in a nutrient-dependent manner”
Yan Cao, Aihong Zhang, Jinyang Cai, Na Yuan, Weiwei Lin, Shengbing Liu, Fei Xu, Lin Song, Xin Li, Yixuan Fang, Zhen Wang, Zhijian Wang, Jian Wang, Han Zhang, Wenli Zhao, Shaoyan Hu, Suping Zhang, Jianrong Wang

 

Pentraxin-3 levels in graft-versus-host disease during allogeneic hematopoietic stem cell transplantation

 Jan-Moritz Doehn, Andreas Winkler, Zoya Kuzmina, Anastasiya Hladik, Hildegard Greinix, Sylvia Knapp, Oliver Robak

The spleen dictates platelet destruction, anti-platelet antibody production, and lymphocyte distribution patterns in a murine model of immune thrombocytopenia
Rukhsana Aslam, Rick Kapur, George B. Segel, Li Guo, Anne Zufferey, Heyu Ni, John W. Semple

Clinical significance and origin of leukocytes that lack HLA-A allele expression in patients with acquired aplastic anemia
Hiroyuki Maruyama, Takamasa Katagiri, Koichi Kashiwase, Takashi Shiina, Aiko Sato-Otsubo, Yoshitaka Zaimoku, Kana Maruyama, Kohei Hosokawa, Ken Ishiyama, Hirohito Yamazaki, Hidetoshi Inoko, Seishi Ogawa, Shinji Nakao

Effects of GlyT1 inhibition on erythropoiesis and iron homeostasis in rats
Michael Winter, Jürgen Funk, Annette Körner, Daniela Alberati, Francois Christen, Georg Schmitt, Bernd Altmann, Andreas Pospischil, Thomas Singer

Characterization of memory B cells from thymus and its impact for DLBCL classification
Kim Steve Bergkvist, Martin Agge Nørgaard, Martin Bøgsted, Alexander Schmitz, Mette Nyegaard, Michael Gaihede, John Bæch, Marie-Louise Grønholdt, Frank Svendsen Jensen, Preben Johansen, Thomas Urup, Tarec C. El-Galaly, Jakob Madsen, Julie Støve Bødker, Karen Dybkær, Hans Erik Johnsen

Alterations of circulating lymphoid committed progenitor cellular metabolism after allogeneic stem cell transplantation in humans
Salomé Glauzy, Régis Peffault de Latour, Isabelle André-Schmutz, Joël Lachuer, Sophie Servais, Gérard Socié, Emmanuel Clave, Antoine Toubert

Calreticulin mutation does not contribute to disease progression in essential thrombocythemia by inhibiting phagocytosis
Shinya Daitoku, Katsuto Takenaka, Takuji Yamauchi, Ayano Yurino, Fumiaki Jinnouchi, Takuya Nunomura, Tetsuya Eto, Tomohiko Kamimura, Masakazu Higuchi, Naoki Harada, Noriyuki Saito, Toshihiro Miyamoto, Hiromi Iwasaki, Koichi Akashi

Spliceosomal component Sf3b1 is essential for hematopoietic differentiation in zebrafish
Adriana De La Garza, Rosannah C. Cameron, Sara Nik, Sara G. Payne, Teresa V. Bowman

Overexpression of LMO2 causes aberrant human T-Cell development in vivo by three potentially distinct cellular mechanisms
Anna-Sophia Wiekmeijer, Karin Pike-Overzet, Martijn H. Brugman, Marja C.J.A. van Eggermond, Martijn Cordes, Edwin F.E. de Haas, Yunlei Li, Edwin Oole, Wilfred F.J. van IJcken, R. Maarten Egeler, Jules P. Meijerink, Frank J.T. Staal

A novel lymphoid progenitor cell population (LSKlow) is restricted by p18INK4c
Fang Dong, Sha Hao, Shihui Ma, Hui Cheng, Yajie Wang, Wen Zhou, Weiping Yuan, Hideo Ema, Tao Cheng