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Posted By Connections Editor,
Wednesday, June 13, 2018
Updated: Tuesday, June 12, 2018
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June
Review
Nisha Narayan, Cameron P. Bracken, Paul G. Ekert
New Methods and Technologies
Naoya Uchida, Juan J. Haro-Mora, Selami Demirci, Atsushi Fujita, Lydia Raines, Matthew M. Hsieh, John F. Tisdale
Stem Cells
Maile K. Hollinger, Valentina Giudice, Nicole A. Cummings, Guillermo Rivell, Hansheng Zhang, Sachiko Kajigaya, Keyvan Keyvanfar, Jichun Chen, Xingmin Feng, Neal S. Young
Transplants
Guillermo Ortí, Jaime Sanz, Irene García-Cadenas, Isabel Sánchez-Ortega, Laura Alonso, Maria José Jiménez, Luisa Sisinni, Carmen Azqueta, Olga Salamero, Isabel Badell, Christelle Ferra, Cristina Diaz de Heredia, Rocio Parody, Miguel Angel Sanz, Jorge Sierra, Jose Luis Piñana, Sergi Querol, David Valcárcel
Omics of Hematopoiesis
Stephen Capone, Kwasi M. Connor, Anthony Colombo, Xin Li, Tim J. Triche Jr., Giridharan Ramsingh
Nonmalignant Hematologic Diseases
Sayantani Sinha, Shankha Subhra Chatterjee, Mayukh Biswas, Arijit Nag, Debasis Banerjee, Rajib De, Amitava Sengupta
Gene Therapy
Niraja M. Dighe, Kang Wei Tan, Lay Geok Tan, Steven S.W. Shaw, Suzanne M.K. Buckley, Dedy Sandikin, Nuryanti Johana, Yi-Wan Tan, Arijit Biswas, Mahesh Choolani, Simon N. Waddington, Michael N. Antoniou, Jerry K.Y. Chan, Citra N.Z. Mattar
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Posted By Connections Editor,
Wednesday, April 11, 2018
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April
Brandon Hadland, Momoko Yoshimoto
Sachith Mettananda, Kevin Clark, Chris A. Fisher, Jackie A. Sloane-Stanley, Richard J. Gibbons, Douglas R. Higgs
Betsabeh Khoramian Tusi, Merav Socolovsky
Yanhong Li, Shuai Zhu, Yuanyuan Zhang, Ting Liu, Linchong Su, Qiuping Zhang, Yubin Luo
Yuemin Gong, Mei Zhao, Wanzhu Yang, Ai Gao, Xiuxiu Yin, Linping Hu, Xiaofang Wang, Jing Xu, Sha Hao, Tao Cheng, Hui Cheng
Lina Quan, Xiuwen Lan, Yuanyuan Meng, Xiuchen Guo, Yiwei Guo, Lina Zhao, Xue Chen, Aichun Liu
Esther Tijchon, Liesbeth van Emst, Laurensia Yuniati, Dorette van Ingen Schenau, Mylène Gerritsen, Laurens T. van der Meer, Owen Williams, Peter M. Hoogerbrugge, Blanca Scheijen, Frank N. van Leeuwen
Ruosi Yao, Danyang Han, Xiaoyang Sun, Yu Xie, Qingyun Wu, Chunling Fu, Yao Yao, Hujun Li, Zhenyu Li, Kailin Xu
Jian-Ming Gu, Shujun Yuan, Derek Sim, Keith Abe, Perry Liu, Martin Rosenbruch, Peter Bringmann, Katalin Kauser
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Posted By Connections Editor,
Wednesday, March 21, 2018
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March
Peter Kurre
Anna Rita Migliaccio
The mirn23a and mirn23b microrna clusters are necessary for proper hematopoietic progenitor cell production and differentiation
Jeffrey L. Kurkewich, Austin Boucher, Nathan Klopfenstein, Ramdas Baskar, Reuben Kapur, Richard Dahl
Hiroshi Yoshida, Hajime Yamada, Wataru Nogami, Keiji Dohi, Tomomi Kurino-Yamada, Koji Sugiyama, Koji Takahashi, Yoshinari Gahara, Motoji Kitaura, Minoru Hasegawa, Itsuki Oshima, Kenji Kuwabara
Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors
Juana Serrano-Lopez, Kalpana Nattamai, Nicholas A. Pease, Miranda S. Shephard, Ashley M. Wellendorf, Mathieu Sertorio, Eric A. Smith, Hartmut Geiger, Susanne I. Wells, Jose A. Cancelas, Lisa M. Privette Vinnedge
Yusuke Tokoro, Yoko Yamada, Shin-ichiro Takayanagi, Tetsuya Hagiwara
Lauren A. Solomon, Carolina R. Batista, Rodney P. DeKoter
Samuel O. Abegunde, Rena Buckstein, Richard A. Wells, Michael J. Rauh
Emmanuel Griessinger, Jacques Vargaftig, Stuart Horswell, David C. Taussig, John Gribben, Dominique Bonnet
Saori Maegawa, Yoshiaki Chinen, Yuji Shimura, Kazuna Tanba, Tomoko Takimoto, Yoshimi Mizuno, Yayoi Matsumura-Kimoto, Saeko Kuwahara-Ota, Taku Tsukamoto, Tsutomu Kobayashi, Shigeo Horiike, Masafumi Taniwaki, Junya Kuroda
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Posted By Connections Editor,
Wednesday, March 21, 2018
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Connie J. Eaves
Allison J. Li, Laura M. Calvin
Comprehensive discovery of noncoding RNAs in acute myeloid leukemia cell transcriptomes
Jin Zhang, Malachi Griffith, Christopher A. Miller, Obi L. Griffith, David H. Spencer, Jason R. Walker, Vincent Magrini, Sean D. McGrath, Amy Ly, Nichole M. Helton, Maria Trissal, Daniel C. Link, Ha X. Dang, David E. Larson, Shashikant Kulkarni, Matthew G. Cordes, Catrina C. Fronick, Robert S. Fulton, Jeffery M. Klco, Elaine R. Mardis, Timothy J. Ley, Richard K. Wilson, Christopher A. Maher
Matilda Billing, Emma Rörby, Maria Dahl, Ulrika Blank, Silja Andradottír, Mats Ehinger, Stefan Karlsson
Katharina Senger, Gina Marka, Karin Soller, Vadim Sakk, Maria Carolina Florian, Hartmut Geiger
Alyssa H. Cull, Brooke Snetsinger, Rena Buckstein, Richard A. Wells, Michael J. Rauh
Bruno Martino, Corrado Mammì, Claudia Labate, Silvia Rodi, Domenica Ielo, Manuela Priolo, Maurizio Postorino, Giovanni Tripepi, Francesca Ronco, Carmelo Laganà, Caterina Musolino, Marianna Greco, Giorgio La Nasa, Giovanni Caocci
Arzu Yalcin, Marlon Kovarbasic, Julius Wehrle, Rainer Claus, Heiko Becker, Mahmoud Abdelkarim, Verena I. Gaidzik, Andrea Schmidts, Ralph Wäsch, Heike L. Pahl, Konstanze Döhner, Lars Bullinger, Justus Duyster, Michael Lübbert, Björn Hackanson
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The slippery slope of hematopoietic stem cell aging
Martin Wahlestedt, David Bryder
MicroRNA-22 controls interferon alpha production and erythroid maturation in response to infectious stress in mice
Claudine S. Kadmon, Cameron T. Landers, Haiyan S. Li, Stephanie S. Watowich, Antony Rodriguez, Katherine Y. King
John G. Noel, Benjamin J. Ramser, Jose A. Cancelas, Francis X. McCormack, Jason C. Gardner
Effects of in vivo deletion of GATA2 in bone marrow stromal cells
Shin Hasegawa, Tohru Fujiwara, Yoko Okitsu, Hiroki Kato, Yuki Sato, Noriko Fukuhara, Yasushi Onishi, Ritsuko Shimizu, Masayuki Yamamoto, Hideo Harigae
Lauren A. Solomon, Carolina R. Batista, Rodney P. DeKoter
Karine Lagacé, Fréderic Barabé, Josée Hébert, Sonia Cellot, Brian T. Wilhelm
Terence A. McGonigle, Amy R. Dwyer, Eloise L. Greenland, Naomi M. Scott, Kevin N. Keane, Philip Newsholme, Helen S. Goodridge, Leonard I. Zon, Fiona J. Pixley, Prue H. Hart
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Posted By Connections Editor,
Friday, September 8, 2017
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August
CBP/Catenin antagonists: Targeting LSCs’ Achilles heel
Yong-Mi Kim, Eun-Ji Gang, Michael Kahn
Reprogramming acute myeloid leukemia into sensitivity for retinoic-acid-driven differentiation
Noortje van Gils, Han J.M.P. Verhagen, Linda Smit
Reciprocal regulation between hepcidin and erythropoiesis and its therapeutic application in erythroid disorders
Caiyi Wang, Zheng Fang, Zesen Zhu, Jing Liu, Huiyong Chen
With me or against me: Tumor suppressor and drug resistance activities of SAMHD1
Nikolas Herold, Sean G. Rudd, Kumar Sanjiv, Juliane Kutzner, Ida Hed Myrberg, Cynthia B.J. Paulin, Thale Kristin Olsen, Thomas Helleday, Jan-Inge Henter, Torsten Schaller
FLT3 ligand regulates thymic precursor cells and hematopoietic stem cells through interactions with CXCR4 and the marrow niche
Kirsten M. Williams, Amber R. Moore, Philip J. Lucas, Juin Wang, Catherine V. Bare, Ronald E. Gress
HIF-1α-stabilizing agent FG-4497 rescues human CD34+ cell mobilization in response to G-CSF in immunodeficient mice
Bianca Nowlan, Kathryn Futrega, Marion E. Brunck, Gail Walkinshaw, Lee E. Flippin, Michael R. Doran, Jean-Pierre Levesque
D816V mutation in the KIT gene activation loop has greater cell-proliferative and anti-apoptotic ability than N822K mutation in core-binding factor acute myeloid leukemia
Ikuko Omori, Hiroki Yamaguchi, Koichi Miyake, Noriko Miyake, Tomoaki Kitano, Koiti Inokuchi
Development of an assay for cellular efflux of pharmaceutically active agents and its relevance to understanding drug interactions
Benigno C. Valdez, Moustapha Hassan, Borje S. Andersson
September
B-cell identity as a metabolic barrier against malignant transformation
Lai N. Chan, Markus Müschen
TAL1 as a master oncogenic transcription factor in T-cell acute lymphoblastic leukemia
Takaomi Sanda, Wei Zhong Leong
Novel tumor-suppressor function of KLF4 in pediatric T-cell acute lymphoblastic leukemia
Ye Shen, Taylor J. Chen, H. Daniel Lacorazza
Lifelong dietary intervention does not affect hematopoietic stem cell function
Seka Lazare, Albertina Ausema, Aaffien C. Reijne, Gertjan van Dijk, Ronald van Os, Gerald de Haan
A novel dual inhibitor of microtubule and Bruton's tyrosine kinase inhibits survival of multiple myeloma and osteoclastogenesis
Manoj K. Pandey, Krishne Gowda, Shen-shu Sung, Thomas Abraham, Tulin Budak-Alpdogan, Giampolo Talamo, Sinisa Dovat, Shantu Amin
PRKCH regulates hematopoietic stem cell function and predicts poor prognosis in acute myeloid leukemia
Shaina N. Porter, Jeffrey A. Magee
Whole-genome analysis reveals unexpected dynamics of mutant subclone development in a patient with JAK2-V617F-positive chronic myeloid leukemia
Ivan Sloma, Maria Teresa Mitjavila-Garcia, Olivier Feraud, Frank Griscelli, Noufissa Oudrhiri, Sanaa El Marsafy, Emilie Gobbo, Dominique Divers, Alexis Proust, David M. Smadja, Christophe Desterke, Annaick Carles, Yusanna Ma, Martin Hirst, Marco A. Marra, Connie J. Eaves, Annelise Bennaceur-Griscelli, Ali G. Turhan
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Posted By Connections Editor,
Tuesday, June 20, 2017
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May
Chromatin priming of genes in development: Concepts, mechanisms and consequences
Constanze Bonifer, Peter N. Cockerill
Induced pluripotent stem cell technology: A window for studying the pathogenesis of acquired aplastic anemia and possible applications
Mahmoud I. Elbadry, J. Luis Espinoza, Shinji Nakao
Hemangioblast, hemogenic endothelium, and primitive versus definitive hematopoiesis
Georges Lacaud, Valerie Kouskoff
Predictive value of pretransplantation molecular minimal residual disease assessment by WT1 gene expression in FLT3-positive acute myeloid leukemia
Anna Candoni, Federico De Marchi, Francesca Zanini, Maria Elena Zannier, Erica Simeone, Eleonora Toffoletti, Alexsia Chiarvesio, Michela Cerno, Carla Filì, Francesca Patriarca, Renato Fanin
Androgen receptor expression in mantle cell lymphoma: Potential novel therapeutic implications
Elahe A. Mostaghel, Paul S. Martin, Stephen Mongovin, Shani Frayo, Ailin Zhang, Kerstin L. Edlefsen, Oliver W. Press, Ajay K. Gopal
Use of ubiquitous, highly heterozygous copy number variants and digital droplet polymerase chain reaction to monitor chimerism after allogeneic haematopoietic stem cell transplantation
John B. Whitlam, Ling Ling, Michael Swain, Tom Harrington, Oksana Mirochnik, Ian Brooks, Sara Cronin, Jackie Challis, Vida Petrovic, Damien L. Bruno, Francoise Mechinaud, Rachel Conyers, Howard Slater
Governing roles for Trib3 pseudokinase during stress erythropoiesis
Arvind Dev, Ruth Asch, Edward Jachimowicz, Nicole Rainville, Ashley Johnson, Emily Greenfest-Allen, Don M. Wojchowski
Impact of TET2 deficiency on iron metabolism in erythroblasts
Kyoko Inokura, Tohru Fujiwara, Kei Saito, Tatsuya Iino, Shunsuke Hatta, Yoko Okitsu, Noriko Fukuhara, Yasushi Onishi, Kenichi Ishizawa, Kazuya Shimoda, Hideo Harigae
Shipping mouse bone marrow: Keep it in the bone
Ani E. Papazian, Youmna S. Kfoury, David T. Scadden
June
Application of vitamin D and vitamin D analogs in acute myelogenous leukemia
Huynh Cao, Yi Xu, Rosalia de Necochea-Campion, David J. Baylink, Kimberly J. Payne, Xiaolei Tang, Christina Ratanatharathorn, Yong Ji, Saied Mirshahidi, Chien-Shing Chen
Role of mTORC1–S6K1 signaling pathway in regulation of hematopoietic stem cell and acute myeloid leukemia
Joydeep Ghosh, Reuben Kapur
The evolving view of the hematopoietic stem cell niche
Isabel Beerman, Tiago C. Luis, Sofie Singbrant, Cristina Lo Celso, Simon Méndez-Ferrer
A defined role for multiple Fanconi anemia gene products in DNA-damage-associated ubiquitination
Winnie Tan, Andrew J. Deans
Rat acute GvHD is Th1 driven and characterized by predominant donor CD4+ T-cell infiltration of skin and gut
Margherita Boieri, Pranali Shah, Dasaradha Jalapothu, Olena Zaitseva, Lutz Walter, Bent Rolstad, Christian Naper, Ralf Dressel, Marit Inngjerdingen
Pharmacological inhibition of LSD1 and mTOR reduces mitochondrial retention and associated ROS levels in the red blood cells of sickle cell disease
Ramasamy Jagadeeswaran, Benjamin A. Vazquez, Muthusamy Thiruppathi, Balaji B. Ganesh, Vinzon Ibanez, Shuaiying Cui, James D. Engel, Alan M. Diamond, Robert E. Molokie, Joseph DeSimone, Donald Lavelle, Angela Rivers
The Calreticulin control of human stress erythropoiesis is impaired by JAK2V617F in polycythemia vera
Mario Falchi, Lilian Varricchio, Fabrizio Martelli, Manuela Marra, Orietta Picconi, Agostino Tafuri, Gabriella Girelli, Vladimir N. Uversky, Anna Rita Migliaccio
Novel roles for podocalyxin in regulating stress myelopoiesis, Rap1a, and neutrophil migration
Pan Li, Aldona A. Karaczyn, Rose McGlauflin, Amanda J. Favreau-Lessard, Edward Jachimowicz, Calvin P. Vary, Kailin Xu, Don M. Wojchowski, Pradeep Sathyanarayana
Targeted deletion of the Hoxa cluster affects B lymphopoiesis through depletion of early lymphoid progenitors
Charles-Étienne Lebert-Ghali, Alexander Thompson, Heather J. Melichar, Janet J. Bijl
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Posted By Connections Editor,
Friday, April 21, 2017
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March
‘Off-the-shelf’ immunotherapy with iPSC-derived rejuvenated cytotoxic T lymphocytes
Miki Ando, Hiromitsu Nakauchi
Preclinical approaches in chronic myeloid leukemia: from cells to systems
Cassie J. Clarke, Tessa L. Holyoake
From the bedside to the bench: new discoveries on blood cell fate and function
Eirini Trompouki, Eugenia Flores-Figueroa, Daniel Lucas, Teresa V. Bowman
Targeting the transcription factor Myb by small-molecule inhibitors
Sagar Uttarkar, Jon Frampton, Karl-Heinz Klempnauer
Immunogenicity of murine mPEG-red blood cells and the risk of anti-PEG antibodies in human blood donors
Yevgeniya Le, Wendy M. Toyofuku, Mark D. Scott
Everolimus restrains the IL-17A-dependent osteoclast-like transdifferentiation of dendritic cells in multiple myeloma
Marco Tucci, Stefania Stucci, Anna Passarelli, Stella D'Oronzo, Franco Silvestris
Variable aldehyde dehydrogenase activity and effects on chemosensitivity of primitive human leukemic cells
Anja Bogen, Christian Buske, Wolfgang Hiddemann, Stefan K. Bohlander, Oliver Christ
MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27 acetylation
Laura Godfrey, Jon Kerry, Ross Thorne, Emmanouela Repapi, James O.J. Davies, Marta Tapia, Erica Ballabio, Jim R. Hughes, Huimin Geng, Marina Konopleva, Thomas A. Milne
Mysm1 expression in the bone marrow niche is not essential for hematopoietic maintenance
Jessica C. Petrov, Anastasia Nijnik
MOZ and BMI1 act synergistically to maintain hematopoietic stem cells
Bilal N. Sheikh, Donald Metcalf, Anne K. Voss, Tim Thomas
April
Donor lymphocyte infusions in AML and MDS: Enhancing the graft-versus-leukemia effect
Guillermo Orti, Pere Barba, Laura Fox, Olga Salamero, Francesc Bosch, David Valcarcel
Polycomb complexes PRC1 and their function in hematopoiesis
Miguel Vidal, Katarzina Starowicz
Kinase signaling and targeted therapy for primary myelofibrosis
Qiong Yang, John D. Crispino, Qiang Jeremy Wen
Mutational analysis of hypermutation-related POLE gene in acute leukemias and lymphomas
Eun Ji Choi, Min Sung Kim, Nam Jin Yoo, Sug Hyung Lee
Analysis of parameters that affect human hematopoietic cell outputs in mutant c-kit-immunodeficient mice
Paul H. Miller, Gabrielle Rabu, Margarita MacAldaz, David J.H.F. Knapp, Alice M.S. Cheung, Kiran Dhillon, Naoto Nakamichi, Philip A. Beer, Leonard D. Shultz, R. Keith Humphries, Connie J. Eaves
Ixazomib suppresses human dendritic cell and modulates murine graft-versus-host disease in a schedule-dependent fashion
Ahmad Samer Al-Homsi, Austin Goodyke, Kelli Cole, Marlee Muilenburg, Michael McLane, Sarah Abdel-Mageed, Yuxin Feng
The BAF45a/PHF10 subunit of SWI/SNF-like chromatin remodeling complexes is essential for hematopoietic stem cell maintenance
Veneta Krasteva, Gerald R. Crabtree, Julie A. Lessard
EphA5 and EphA7 forward signaling enhances human hematopoietic stem and progenitor cell maintenance, migration, and adhesion via Rac1 activation
Thao M. Nguyen, Agnieszka Arthur, Andrew C.W. Zannettino, Stan Gronthos
Impairment of fetal hematopoietic stem cell function in the absence of Fancd2
Sakiko Suzuki, Ronny R. Racine, Nathan A. Manalo, Sharon B. Cantor, Glen D. Raffel
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Posted By Connections Editor,
Tuesday, February 28, 2017
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January
Using zebrafish models of leukemia to streamline drug screening and discovery
Adam P. Deveau, Victoria L. Bentley, Jason N. Berman
Novel strategies of adoptive immunotherapy: How natural killer cells may change the treatment of elderly patients with acute myeloblastic leukemia
Roberto M. Lemoli, Sarah Parisi, Antonio Curti
Tumor necrosis factor α in the onset and progression of leukemia
Xiaoxi Zhou, Zhuoya Li, Jianfeng Zhou
Clinical-grade regulatory T cells: Comparative analysis of large-scale expansion conditions
Sarvari Velaga, Christina Alter, Ulrike Dringenberg, Christina T. Thiesler, Sandra Kuhs, Sven Olek, Sya N. Ukena, Anke Franzke
AC220 and AraC cause differential inhibitory dynamics in patient-derived M5-AML with FLT3-ITD and, thus, ultimately distinct therapeutic outcomes
Xiaoyu An, Jinping Liu, Na Wang, Di Wang, Liang Huang, Likun Zhang, Jie Cai, Jean-Pierre Wery, Demin Zhou, Jianfeng Zhou, Qi-Xiang Li
Constitutive Kit activity triggers B-cell acute lymphoblastic leukemia-like disease in mice
Robin R. Weidemann, Rayk Behrendt, Kristina B. Schoedel, Werner Müller, Axel Roers, Alexander Gerbaulet
Alterations in the bone marrow microenvironment may elicit defective hematopoiesis: a comparison of aplastic anemia, chronic myeloid leukemia, and normal bone marrow
Meerim Park, Chan-Jeoung Park, Young Wook Cho, Seongsoo Jang, Jung-Hee Lee, Je-Hwan Lee, Kyoo-Hyung Lee, Young Ho Lee
The AMP-activated protein kinase beta 1 subunit modulates erythrocyte integrity
Emma L. Cambridge, Zoe McIntyre, Simon Clare, Mark J. Arends, David Goulding, Christopher Isherwood, Susana S. Caetano, Carmen Ballesteros Reviriego, Agnieszka Swiatkowska, Leanne Kane, Katherine Harcourt, The Sanger Mouse Genetics Project, David J. Adams, Jacqueline K. White, Anneliese O. Speak
Sustained enhancement of OCTN1 transporter expression in association with hydroxyurea induced γ-globin expression in erythroid progenitors
Aisha L. Walker, Solomon F. Ofori-Acquah
Pharmacological inhibition of AKT activity in human CD34+ cells enhances their ability to engraft immunodeficient mice
Sisi Chen, Rui Gao, Michihiro Kobayashi, Hao Yu, Chonghua Yao, Reuben Kapur, Mervin C. Yoder, Yan Liu
Proinflammatory signals are insufficient to drive definitive hematopoietic specification of human HSCs in vitro
Alessandra Giorgetti, Julio Castaño, Clara Bueno, Rafael Díaz de la Guardia, Mario Delgado, Anna Bigas, Lluis Espinosa, Pablo Menendez
February
Ikaros: Exploiting and targeting the hematopoietic stem cell niche in B-progenitor acute lymphoblastic leukemia
Michelle L. Churchman, Charles G. Mullighan
Granulocyte colony-stimulating factor receptor signaling in severe congenital neutropenia, chronic neutrophilic leukemia, and related malignancies
Pankaj Dwivedi, Kenneth D. Greis
Transcriptional activation by MLL fusion proteins in leukemogenesis
Akihiko Yokoyama
Dynamic variation of CD5 surface expression levels within individual chronic lymphocytic leukemia clones
Rachael J.M. Bashford-Rogers, Anne L. Palser, Clare Hodkinson, Joanna Baxter, George A. Follows, George S. Vassiliou, Paul Kellam
Genetically re-engineered K562 cells significantly expand and functionally activate cord blood natural killer cells: Potential for adoptive cellular immunotherapy
Janet Ayello, Jessica Hochberg, Allyson Flower, Yaya Chu, Laxmi V. Baxi, William Quish, Carmella van de Ven, Mitchell S. Cairo
Lenalidomide enhances the function of dendritic cells generated from patients with multiple myeloma
Manh-Cuong Vo, Truc Anh-NguyenThi, Hyun-Ju Lee, Thanh-Nhan Nguyen-Pham, Thangaraj Jaya Lakshmi, Sung-Hoon Jung, Hyeoung-Joon Kim, Je-Jung Lee
MiR-17-92 represses PTPROt and PP2A phosphatases and amplifies tonic BCR signaling in DLBCL cells
Ewa Jablonska, Patryk Gorniak, Maciej Szydlowski, Tomasz Sewastianik, Emilia Bialopiotrowicz, Anna Polak, Krzysztof Warzocha, Przemyslaw Juszczynski
AML1–ETO promotes SIRT1 expression to enhance leukemogenesis of t(8;21) acute myeloid leukemia
Lei Zhou, Qian Wang, Xiaosu Chen, Lin Fu, Xiaodong Zhang, Lijun Wang, Ailing Deng, Dandan Li, Jing Liu, Na Lv, Lili Wang, Yonghui Li, Daihong Liu, Li Yu, Liping Dou
Csk-binding protein controls red blood cell development via regulation of Lyn tyrosine kinase activity
Janice H.C. Plani-Lam, Neli S. Slavova-Azmanova, Nicole Kucera, Alison Louw, Jiulia Satiaputra, Peter Singer, Kong-Peng Lam, Margaret L. Hibbs, Evan Ingley
HIF1α-induced PDGFRβ signaling promotes developmental HSC production via IL-6 activation
Sung-Eun Lim, Virginie Esain, Wanda Kwan, Lindsay N. Theodore, Mauricio Cortes, Isaura M. Frost, Sarah Y. Liu, Trista E. North
Erratum to “Effect of roflumilast, novel phosphodiesterase-4 inhibitor, on lung chronic graft-versus-host disease in mice”
Sei Won Kim, Ji Young Lim, Chin Kook Rhee, Ji Hye Kim, Chan Kwon Park, Tae Jung Kim, Chul Soo Cho, Chang Ki Min, Hyoung Kyu Yoon
Erratum to “Autophagy regulates the cell cycle of mouse HSPCs in a nutrient-dependent manner”
Yan Cao, Aihong Zhang, Jinyang Cai, Na Yuan, Weiwei Lin, Shengbing Liu, Fei Xu, Lin Song, Xin Li, Yixuan Fang, Zhen Wang, Zhijian Wang, Jian Wang, Han Zhang, Wenli Zhao, Shaoyan Hu, Suping Zhang, Jianrong Wang
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Posted By Connections Editor,
Wednesday, December 14, 2016
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November
Delivery of RNA-based molecules to human hematopoietic stem and progenitor cells for modulation of gene expression
Yvonne Diener, Andreas Bosio, Ute Bissels
Mechanisms of heparanase inhibitors in cancer therapy
Benjamin Heyman, Yiping Yang
Improving the safety of T-Cell therapies using an inducible caspase-9 gene
Xiaoou Zhou, Malcolm K. Brenner
Precision in donor selection: Identifying ideal stem-cell donors through their T cells
Adam Widman, Ran Reshef
Longitudinal analyses of leukemia-associated antigen-specific CD8+ T cells in patients after allogeneic stem cell transplantation
Elke Rücker-Braun, Cornelia S. Link, Maria Schmiedgen, Antje Tunger, Petra Vizjak, Raphael Teipel, Rebekka Wehner, Denise Kühn, Yannik F. Fuchs, Uta Oelschlägel, Lothar Germeroth, Marc Schmitz, Martin Bornhäuser, Johannes Schetelig, Falk Heidenreich
A genome-wide association study by ImmunoChip reveals potential modifiers in myelodysplastic syndromes
Fabrice Danjou, Claudio Fozza, Magdalena Zoledziewska, Antonella Mulas, Giovanna Corda, Salvatore Contini, Fausto Dore, Antonio Galleu, Anna Angela Di Tucci, Giovanni Caocci, Eleonora Gaviano, Giancarlo Latte, Attilio Gabbas, Paolo Casula, Lucia Gemma Delogu, Giorgio La Nasa, Emanuele Angelucci, Francesco Cucca, Maurizio Longinotti
Complement cascade gene expression defines novel prognostic subgroups of acute myeloid leukemia
Isabelle Laverdière, Meaghan Boileau, Tobias Herold, Janusz Rak, Wolfgang E. Berdel, Bernhard Wörmann, Wolfgang Hiddemann, Karsten Spiekermann, Stefan K. Bohlander, Kolja Eppert
JAK2 V617F stimulates proliferation of erythropoietin-dependent erythroid progenitors and delays their differentiation by activating Stat1 and other nonerythroid signaling pathways
Jiahai Shi, Bingbing Yuan, Wenqian Hu, Harvey Lodish
Quantitative proteomic analysis and comparison of two bone marrow stromal cell lines using the SILAC method
Xiang Li, Ting Wan, Sijie Zhang, Dongliang Li, Xiaofeng Han
Human blood cell levels of 5-hydroxymethylcytosine (5hmC) decline with age, partly related to acquired mutations in TET2
Manuel Buscarlet, Alain Tessier, Sylvie Provost, Luigina Mollica, Lambert Busque
Uncoupling protein 2 deficiency results in higher neutrophil counts and lower B-cell counts during aging in mice
Christin Kretzschmar, Catrin Roolf, Katrin Timmer, Anett Sekora, Gudrun Knübel, Hugo Murua Escobar, Robert Jaster, Sarah Müller, Georg Fuellen, Rüdiger Köhling, Christian Junghanss
Tunneling nanotubes mediate the transfer of stem cell marker CD133 between hematopoietic progenitor cells
Doreen Reichert, Julia Scheinpflug, Jana Karbanová, Daniel Freund, Martin Bornhäuser, Denis Corbeil
December
NOX-driven ROS formation in cell transformation of FLT3-ITD-positive AML
Ashok Kumar Jayavelu, Jennifer N. Moloney, Frank-D. Böhmer, Thomas G. Cotter
Variegated RHOA mutations in human cancers
Keisuke Kataoka, Seishi Ogawa
Translating leukemia stem cells into the clinical setting: Harmonizing the heterogeneity
Breann Yanagisawa, Gabriel Ghiaur, B. Douglas Smith, Richard J. Jones
Preclinical rationale for TGF-β inhibition as a therapeutic target for the treatment of myelofibrosis
Ilaria Ceglia, Amylou C. Dueck, Francesca Masiello, Fabrizio Martelli, Wu He, Giulia Federici, Emanuel F. Petricoin III, Ann Zeuner, Camelia Iancu-Rubin, Rona Weinberg, Ronald Hoffman, John Mascarenhas, Anna Rita Migliaccio
Metformin inhibits JAK2V617F activity in MPN cells by activating AMPK and PP2A complexes containing the B56α subunit
Ichiro Kawashima, Keita Kirito
MicroRNA-155 is upregulated in MLL-rearranged AML but its absence does not affect leukemia development
Edith Schneider, Anna Staffas, Linda Röhner, Kathrin Krowiorz, Michael Heuser, Konstanze Döhner, Lars Bullinger, Hartmut Döhner, Linda Fogelstrand, Arefeh Rouhi, Florian Kuchenbauer, Lars Palmqvist
Immunological properties of bone marrow microenvironment 1 year after allogeneic hematopoietic stem cell transplantation
Agnieszka Ciomber, Iwona Mitrus, Wojciech Fidyk, Andrzej Smagur, Agata Chwieduk, Magdalena Glowala-Kosinska, Tomasz Czerw, Małgorzata Sobczyk-Kruszelnicka, Włodzimierz Mendrek, Maria Sadus-Wojciechowska, Jacek Najda, Jerzy Holowiecki, Sebastian Giebel
Primary cilia are present on human blood and bone marrow cells and mediate Hedgehog signaling
Mohan Singh, Parvesh Chaudhry, Akil A. Merchant
Loss of ASXL1 triggers an apoptotic response in human hematopoietic stem and progenitor cells
Susan Hilgendorf, Hendrik Folkerts, Jan Jacob Schuringa, Edo Vellenga
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Posted By Connections Editor,
Tuesday, November 1, 2016
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Pentraxin-3 levels in graft-versus-host disease during allogeneic hematopoietic stem cell transplantation
Jan-Moritz Doehn, Andreas Winkler, Zoya Kuzmina, Anastasiya Hladik, Hildegard Greinix, Sylvia Knapp, Oliver Robak
The spleen dictates platelet destruction, anti-platelet antibody production, and lymphocyte distribution patterns in a murine model of immune thrombocytopenia
Rukhsana Aslam, Rick Kapur, George B. Segel, Li Guo, Anne Zufferey, Heyu Ni, John W. Semple
Clinical significance and origin of leukocytes that lack HLA-A allele expression in patients with acquired aplastic anemia
Hiroyuki Maruyama, Takamasa Katagiri, Koichi Kashiwase, Takashi Shiina, Aiko Sato-Otsubo, Yoshitaka Zaimoku, Kana Maruyama, Kohei Hosokawa, Ken Ishiyama, Hirohito Yamazaki, Hidetoshi Inoko, Seishi Ogawa, Shinji Nakao
Effects of GlyT1 inhibition on erythropoiesis and iron homeostasis in rats
Michael Winter, Jürgen Funk, Annette Körner, Daniela Alberati, Francois Christen, Georg Schmitt, Bernd Altmann, Andreas Pospischil, Thomas Singer
Characterization of memory B cells from thymus and its impact for DLBCL classification
Kim Steve Bergkvist, Martin Agge Nørgaard, Martin Bøgsted, Alexander Schmitz, Mette Nyegaard, Michael Gaihede, John Bæch, Marie-Louise Grønholdt, Frank Svendsen Jensen, Preben Johansen, Thomas Urup, Tarec C. El-Galaly, Jakob Madsen, Julie Støve Bødker, Karen Dybkær, Hans Erik Johnsen
Alterations of circulating lymphoid committed progenitor cellular metabolism after allogeneic stem cell transplantation in humans
Salomé Glauzy, Régis Peffault de Latour, Isabelle André-Schmutz, Joël Lachuer, Sophie Servais, Gérard Socié, Emmanuel Clave, Antoine Toubert
Calreticulin mutation does not contribute to disease progression in essential thrombocythemia by inhibiting phagocytosis
Shinya Daitoku, Katsuto Takenaka, Takuji Yamauchi, Ayano Yurino, Fumiaki Jinnouchi, Takuya Nunomura, Tetsuya Eto, Tomohiko Kamimura, Masakazu Higuchi, Naoki Harada, Noriyuki Saito, Toshihiro Miyamoto, Hiromi Iwasaki, Koichi Akashi
Spliceosomal component Sf3b1 is essential for hematopoietic differentiation in zebrafish
Adriana De La Garza, Rosannah C. Cameron, Sara Nik, Sara G. Payne, Teresa V. Bowman
Overexpression of LMO2 causes aberrant human T-Cell development in vivo by three potentially distinct cellular mechanisms
Anna-Sophia Wiekmeijer, Karin Pike-Overzet, Martijn H. Brugman, Marja C.J.A. van Eggermond, Martijn Cordes, Edwin F.E. de Haas, Yunlei Li, Edwin Oole, Wilfred F.J. van IJcken, R. Maarten Egeler, Jules P. Meijerink, Frank J.T. Staal
A novel lymphoid progenitor cell population (LSKlow) is restricted by p18INK4c
Fang Dong, Sha Hao, Shihui Ma, Hui Cheng, Yajie Wang, Wen Zhou, Weiping Yuan, Hideo Ema, Tao Cheng
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