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Inside this Issue: Nov/Dec

Posted By Connections Editor, Wednesday, December 14, 2016


Delivery of RNA-based molecules to human hematopoietic stem and progenitor cells for modulation of gene expression 

Yvonne Diener, Andreas Bosio, Ute Bissels

Mechanisms of heparanase inhibitors in cancer therapy
Benjamin Heyman, Yiping Yang

Improving the safety of T-Cell therapies using an inducible caspase-9 gene
Xiaoou Zhou, Malcolm K. Brenner

Precision in donor selection: Identifying ideal stem-cell donors through their T cells
Adam Widman, Ran Reshef

Longitudinal analyses of leukemia-associated antigen-specific CD8+ T cells in patients after allogeneic stem cell transplantation
Elke Rücker-Braun, Cornelia S. Link, Maria Schmiedgen, Antje Tunger, Petra Vizjak, Raphael Teipel, Rebekka Wehner, Denise Kühn, Yannik F. Fuchs, Uta Oelschlägel, Lothar Germeroth, Marc Schmitz, Martin Bornhäuser, Johannes Schetelig, Falk Heidenreich

A genome-wide association study by ImmunoChip reveals potential modifiers in myelodysplastic syndromes
Fabrice Danjou, Claudio Fozza, Magdalena Zoledziewska, Antonella Mulas, Giovanna Corda, Salvatore Contini, Fausto Dore, Antonio Galleu, Anna Angela Di Tucci, Giovanni Caocci, Eleonora Gaviano, Giancarlo Latte, Attilio Gabbas, Paolo Casula, Lucia Gemma Delogu, Giorgio La Nasa, Emanuele Angelucci, Francesco Cucca, Maurizio Longinotti

Complement cascade gene expression defines novel prognostic subgroups of acute myeloid leukemia

Isabelle Laverdière, Meaghan Boileau, Tobias Herold, Janusz Rak, Wolfgang E. Berdel, Bernhard Wörmann, Wolfgang Hiddemann, Karsten Spiekermann, Stefan K. Bohlander, Kolja Eppert

JAK2 V617F stimulates proliferation of erythropoietin-dependent erythroid progenitors and delays their differentiation by activating Stat1 and other nonerythroid signaling pathways
Jiahai Shi, Bingbing Yuan, Wenqian Hu, Harvey Lodish

Quantitative proteomic analysis and comparison of two bone marrow stromal cell lines using the SILAC method
Xiang Li, Ting Wan, Sijie Zhang, Dongliang Li, Xiaofeng Han

Human blood cell levels of 5-hydroxymethylcytosine (5hmC) decline with age, partly related to acquired mutations in TET2

Manuel Buscarlet, Alain Tessier, Sylvie Provost, Luigina Mollica, Lambert Busque

Uncoupling protein 2 deficiency results in higher neutrophil counts and lower B-cell counts during aging in mice
Christin Kretzschmar, Catrin Roolf, Katrin Timmer, Anett Sekora, Gudrun Knübel, Hugo Murua Escobar, Robert Jaster, Sarah Müller, Georg Fuellen, Rüdiger Köhling, Christian Junghanss

Tunneling nanotubes mediate the transfer of stem cell marker CD133 between hematopoietic progenitor cells
Doreen Reichert, Julia Scheinpflug, Jana Karbanová, Daniel Freund, Martin Bornhäuser, Denis Corbeil



NOX-driven ROS formation in cell transformation of FLT3-ITD-positive AML 

Ashok Kumar Jayavelu, Jennifer N. Moloney, Frank-D. Böhmer, Thomas G. Cotter 

Variegated RHOA mutations in human cancers 
Keisuke Kataoka, Seishi Ogawa 

Translating leukemia stem cells into the clinical setting: Harmonizing the heterogeneity 
Breann Yanagisawa, Gabriel Ghiaur, B. Douglas Smith, Richard J. Jones 
Preclinical rationale for TGF-β inhibition as a therapeutic target for the treatment of myelofibrosis 
Ilaria Ceglia, Amylou C. Dueck, Francesca Masiello, Fabrizio Martelli, Wu He, Giulia Federici, Emanuel F. Petricoin III, Ann Zeuner, Camelia Iancu-Rubin, Rona Weinberg, Ronald Hoffman, John Mascarenhas, Anna Rita Migliaccio 
Metformin inhibits JAK2V617F activity in MPN cells by activating AMPK and PP2A complexes containing the B56α subunit 
Ichiro Kawashima, Keita Kirito 
MicroRNA-155 is upregulated in MLL-rearranged AML but its absence does not affect leukemia development 
Edith Schneider, Anna Staffas, Linda Röhner, Kathrin Krowiorz, Michael Heuser, Konstanze Döhner, Lars Bullinger, Hartmut Döhner, Linda Fogelstrand, Arefeh Rouhi, Florian Kuchenbauer, Lars Palmqvist 
Immunological properties of bone marrow microenvironment 1 year after allogeneic hematopoietic stem cell transplantation 
Agnieszka Ciomber, Iwona Mitrus, Wojciech Fidyk, Andrzej Smagur, Agata Chwieduk, Magdalena Glowala-Kosinska, Tomasz Czerw, Małgorzata Sobczyk-Kruszelnicka, Włodzimierz Mendrek, Maria Sadus-Wojciechowska, Jacek Najda, Jerzy Holowiecki, Sebastian Giebel 
Primary cilia are present on human blood and bone marrow cells and mediate Hedgehog signaling 
Mohan Singh, Parvesh Chaudhry, Akil A. Merchant 
Loss of ASXL1 triggers an apoptotic response in human hematopoietic stem and progenitor cells 
Susan Hilgendorf, Hendrik Folkerts, Jan Jacob Schuringa, Edo Vellenga 


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