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Director: Louise Purton, PhD

Posted By Administration, Wednesday, September 1, 2010
Updated: Tuesday, February 8, 2011

Louise Purton is senior research fellow at St. Vincent's Institute of Medical Research and the University of Melbourne. She is also an associate director at St. Vincent's. Research in her laboratory is focused on understanding how HSCs are regulated, and determining the roles of the bone marrow microenvironment in regulating haemopoietic diseases, including leukaemia. Dr. Purton received her bachelor's and doctoral degrees in physiology from the University of Melbourne and did a post doc in hematology/oncology at the Fred Hutchinson Cancer Research Center, Seattle, Washington USA.

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Treasurer: Tao Cheng, MD

Posted By Administration, Wednesday, September 1, 2010
Updated: Tuesday, February 8, 2011

Professor Tao Cheng is the scientific director at the Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College, director of the State Key Laboratory for Experimental Hematology and the founding director of the Center for Stem Cell Medicine at CAMS in China. He received his medical degree from the Second Military Medical University in Shanghai, China, followed by his residency in internal medicine and clinical fellowship in hematology at Changhai Hospital, Shanghai. Dr. Cheng did his postdoctoral research training at the Hipple Cancer Research Center, Dayton, Ohio and Massachusetts General Hospital, Boston before moving to Harvard University and the University of Pittsburgh to teach.

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Featured Member: Gerald de Haan, PhD

Posted By ISEH Headquarters, Tuesday, June 1, 2010
Updated: Tuesday, January 11, 2011

Gerald de Haan, PhD
ISEH Vice President

Dr. Gerald de Haan is scientific director for ERIBA (European Institute on the Biology of Aging) and professor in the Department of Stem Cell Biology at the University Medical Center Groningen in the Netherlands. As ISEH vice president, he is poised to succeed Dr. David Scadden as president in the 2011-2012 term. Dr. de Haan became enthralled with hematology in his undergraduate years at the University of Groningen in the Netherlands in the late 1980s.
"As an undergraduate biology student, I spent time in Cameroon to study various aspects of malaria immunology,” he recounts. "Ever since then, I have been fascinated by blood biology. When I was offered a PhD position to work on red blood cell kinetics, this seemed like a very logical choice. I have not regretted this decision a single day.”
The University of Groningen and the University Medical Center Groningen decided several years ago to focus their research, education, and care activities on healthy aging. An important component of the strategic plan was to develop a strong research institute, focusing on the biology of aging, on the university premises – ERIBA. ERIBA research investigators are concerned with molecular mechanisms that are likely to contribute to cellular and organismal aging. These may range from chromosome biology (telomeres, DNA repair, sister chromatid differentiation and separation), regenerative medicine (self-renewal, reprogramming, cell fate decisions), protein folding (translation, aggregation, protein modifications, chaperones), energy metabolism (metabolomics, nutrition, oxygen radicals, mitochondria), immunity (immunesenescence, memory, clonality) to trancriptional regulation (histone and DNA modifications, nuclear transport).
The challenges – and the opportunities – of developing ERIBA are many.
"It is challenging to find the proper balance between staying involved in day-to-day activities in the lab and spending time to make sure we secure enough funds to keep the lab going,” Dr. de Haan shares. "These latter activities obviously include grant writing and travelling. Also, it is not trivial to find the best people for the various projects that we are involved in. We try to recruit our PhD students from those that spend a rotation on our lab, and therefore we need to do our best to attract good students.”

ISEH is an important part of Dr. de Haan’s career development.
"My first ISEH meeting was 1992 in Providence, R.I.,” he explains. "It was great to meet all those people whose papers I had read. This was the time when labs were chasing crucial growth factors and their receptors. It was a highly stimulating experience at a time halfway through my PhD project. It was also the occasion where I first met my later postdoctoral supervisor, Gary Van Zant.” Truly devoted to his science, Dr. de Haan acknowledges that it is important to spend time away from the lab and its responsibilities. "I spend most of my non-science hours with my family, which means that many of my weekends are filled with watching field hockey games,” Dr. de Haan shares. "I need those family moments to stay fresh, and would find it very difficult to perform well in science without.”

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Featured Member: David Scadden, MD

Posted By ISEH Headquarters, Thursday, April 1, 2010
Updated: Friday, October 1, 2010

David Scadden, MD
2010-2011 ISEH President

Dr. David Scadden is the Gerald and Darlene Jordan Professor of Medicine at Harvard University. He and Professor Douglas Melton founded and jointly direct the Harvard Stem Cell Institute which is the largest institute dedicated to bringing stem cell biology to medical care in the world. With Professor Melton, Professor Scadden founded and co-chairs the Department of Stem Cell and Regenerative Biology at Harvard University, the first department to span faculties in Harvard's 371-year history.
He is a hematologist/oncologist and directs the Center for Regenerative Medicine at the Massachusetts General Hospital (MGH) while also chairing the hematologic malignancies program in the MGH Cancer Center.
He is an expert on the medical applications of stem cell biology with a particular emphasis on their use in the settings of cancer and AIDS. He has published more than 250 scientific papers and book chapters, and his laboratory has made fundamental contributions regarding how the stem cell niche regulates stem cell function, in defining the molecules limiting stem cell growth, and in discovering a molecular basis for stem cell aging.
Dr. Scadden is the recipient of numerous honors including membership in the Institute of Medicine of the National Academies of Science and awards from the Doris Duke Charitable Trust, the Ellison Medical Foundation, the Burroughs Wellcome Fund, and the Leukemia and Lymphoma Society.
He has served or serves on the Board of Scientific Counselors for the National Cancer Institute, the Board of External Experts for the National Heart, Lung, and Blood Institute, Board of Directors of the International Society for Stem Cell Research, and ISEH. He is an associate member of the Broad Institute of Harvard and MIT. He serves on multiple editorial boards and scientific advisory boards and is a scientific founder of Fate Therapeutics, a private biotechnology company.

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Featured Member: Toshio Suda, MD

Posted By ISEH Headquarters, Thursday, April 1, 2010
Updated: Friday, October 1, 2010

Toshio Suda, MD
2009-2010 ISEH President

Dr. Toshio Suda is professor of developmental biology in the Sakaguchi laboratory in the School of Medicine at Keio University. He became enchanted by the secrets of hematopoiesis when studying in Dr. Makio Ogawa's lab at the Medical University of South Carolina in Charleston and chose his life's work. The two proposed a stochastic model in the differentiation of stem cells, a classical work showing the independent differentiation of stem cells from growth factors.
Dr. Suda identified the niche for hematopoietic stem cells and subsequently established the new field of oxidative stress and stem cell aging. The interaction of stem cells and niches is one of the hot topics in stem cell biology today.

In addition to his efforts at Keio Univeristy, Dr. Suda serves the field through professional societies and publications, such as his role as ISEH president and Scientific Program Committee member, and member of the International Society of Stem Cell Research. He sits on the editorial boards of several publications including Blood (American Society for Hematology), Journal of Experimental Medicine, Cell Stem Cell, and Stem Cells. He is editor-in-chief of the International Journal of Hematology (Japanese Society of Hematology).
Dr. Suda values his ISEH participation. "ISEH is a rather small international meeting where we can focus on in-depth discussion of timely topics. I appreciate the friendly atmosphere and look forward to reuniting with professional friends. At the Melbourne meeting, I am excited to once again see Dr. D. Metcalf, whose work on hemopoietic colonies taught me many things early in my career."
When not involved in his scientific pursuits, Dr. Suda is quite interested in history and would like to furthur understand ancient script and literature.

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8/23/2018 » 8/26/2018
ISEH 47th Annual Meeting - Los Angeles, CA

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