April 2013

About ISEH

The mission of ISEH is to promote the scientific knowledge and clinical application of basic hematology, immunology, stem cell research, cell and gene therapy, and all related aspects through research, publications, discussion, support of young investigators and organization of scientific meetings.

Table of Contents

Annual Meeting News
News from the Field
Member Profile
Society News
Don't Miss These Meetings
Experimental Hematology
Bring Your Case
Members' Corner

Editor's Note: Carolina Abramovich, PhD

Starting from this issue, we will publish a new section called "Bring your case". This is a forum to broadcast a problem and crowd source our members for fast and efficient solutions. In this issue, Drs. I.E. Sommer and D.W. van Bekkum are calling for case histories of BMT in patients with coincident schizophrenia.

If you would like to share your eminent professional achievements with your colleagues, or have creative ideas and commentaries for the content of future newsletters, please contact me by email at exphem@iseh.org.

Annual Meeting News

Vienna meeting highlights and scientific program featured

ISEH 42nd Annual Scientific Meeting
22-25 August, 2013
The Imperial Riding School Renaissance Hotel
Vienna, Austria

Meeting Highlights Online!

Registration group discounts available!

Sending 5 or more attendees from your facility? Take advantage of our group discount rates of $45USD or more per person. Learn more on how you can save on this exclusive scientific meeting.

Scientific Program Feature: Donald Metcalf Award Lecture:
Making and Improving the Function of Adult Blood Stem Cells

Leonard I. Zon, M.D.
Grousbeck Professor of Pediatric Medicine, Harvard Medical School
Investigator, Howard Hughes Medical Institute
Director of the Stem Cell Program, Children’s Hospital Boston
Read more on website

News From the Field

News roundup: April 2013

A collection of industry, policy, government and other hot news from the field of hematology and stem cell.

Stem Cell Agency Banks on $32 Million New Approach to Advance Research

Quest for Cures: The Leukemia & Lymphoma Society Seeks to Fund Three Critical Areas of Blood Cancer Research

Pfizer’s BOSULIF® (bosutinib) Receives Conditional Marketing Authorization from the European Commission

FRC's Dr. David Prentice Congratulates Kansas Senate for Passing Ethical Stem Cell Therapy Bill

U.K. Agency Cautiously Endorses Mitochondria Replacement

Stem-Cell Ruling Riles Researchers

Retina Institute Japan and Dainippon Sumitomo Pharma Form a Capital Alliance towards the Development of Nobel Prize Winning iPS Cell Technology

Cord Blood Registry Is Advancing Regenerative Medicine Research at Exciting Pace

Minerva Biotechnologies Announces Major Breakthrough in Human Stem Cell Research

Promising Stem Cell Therapy for Leukemia Patients

Member Profile

Meet Dr. David Traver, Associate Editor of Experimental Hematology

Dr. David Traver is a professor and researcher in the Department of Cellular and Molecular Medicine at the University of California, San Diego. He has been in the field of hematopoietic stem and progenitor cell biology for 19 years, and an ISEH member for more than a decade. Dr. Traver’s lab is interested in the formation and function of hematopoietic stem cells (HSCs), and how their progeny provide immunity in the young animal. While most of his lab’s studies are conducted in zebrafish, they have recently reinitiated studies in the mouse embryo and in human ES cells. Read more on website

Society News

Top 5 reasons to be an ISEH member....

Reason number 5 – Reduced registration rates to the ISEH flagship Annual Scientific Meeting in Vienna, Austria. Read more on website

Online Education Starts 4 June

Mark your calendars and register now for the first in a series of three webinars developed by ISEH.

Combinatorial Transcriptional Control of Blood Stem and Progenitor Cells: Presented by Berthold Göttgens, PhD, Professor of Molecular Haematology at the Cambridge Institute for Medical Research. Read more on website

Don't Miss These Meetings

New York and Stockholm Host Notable Meetings

The Bone Marrow Niche, Stem Cells, and Leukemia: Impact of Drugs, Chemicals, and the Environment-New York: May 29 - 31, 2013

The 18thCongress of EHA- Stockholm, Sweden: June 13-16, 2013
Read more on website

Experimental Hematology

Experimental Hematology offers fast publication time

Experimental Hematology offers one of the fastest publication times in the field
Read more on website

Inside the March and April 2013 issues

Take a quick tour of the March and April issues and get a feel for the publication's cutting-edge scientific content. Read the full issues online.

In this Issue – March 2013

The mitochondrial redox environment during erythroid development affects mitochondria-less mature red blood cells
Mohanty et al.

Acute lymphoblastic leukemia cells come out of the bone marrow protective niche for increased sensitivity to chemotherapy
Welschinger et al.

Mechanistic insights provide scientific justification for the use of Histone Deacetylase Inhibitors in Myeloproliferative Neoplasms
Gao et al., and Caldaza et al.

In this Issue – April 2013

Gene Set Control Analysis, a new bioinformatic tool to enhance our understanding of blood cell differentiation

Joshi et al

Novel strategy to generate engineered T cell precursors for immunotherapy
Liu et al.

Cord blood-derived MSC: a potential tool to accelerate bone marrow recovery after ionizing radiation
Shim et al.

A modified high dose cyclophosphamide regime that could lower the cost of treatment of patients with several aplastic anemia
Zhang et al.

Regular and fast-track submissions are encouraged

The publishing team seeks manuscripts, reviews, perspectives and letters to the editor describing basic in vitro and in vivo research centered on normal and malignant hematopoiesis, as well as non-malignant hematologic diseases. Read more on website

Bring your case

Call for case histories of BMT in patients with coincident schizophrenia

I.E.Sommer and D.W. van Bekkum

Recently, the case for an immune component in the etiology of schizophrenia has re-gained support (1, 2), leading to randomized controlled-trials to explore treatment with immunosuppressants and anti-inflammatory drugs (3). Both post-mortem (4) and in-vivo studies (5,6) provided indications for an increased pro-inflammatory status in the brain of patients with recent onset schizophrenia.Read more on website


Editors Pick: New Career opportunities available

Laboratory Section Chief- Hematology (Visalia, California)

Manager Specialty Business (Hematology/Neurology) (Wayne, New Jersey)

Study Medical Expert of Hematology(Montville, New Jersey)

Postdoctoral Fellow in Stem Cells and Cancer (Beijing, China)

Postdoctoral position in hematopoietic stem cell biology (Paris, France)

Physician Scientist, Stem Cell Biology and Pediatric Stem Cell Transplant Research (Cleveland, Ohio)

Members' Corner

ISEH recognizes Shalin Naik

Congratulations to Shalin Naik for the publication in Nature of his first authored paper " Diverse and heritable lineage imprinting of early haematopoietic progenitors". The manuscript was published Online on 3 April.

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