Print Page   |   Contact Us   |   Sign In   |   Become a Member
Site Search
ISEH Webinar: Epigenetic regulation of normal and malignant hematopoiesis
Tell a Friend About This EventTell a Friend
 

In this webinar we will hear from the experts Professor Margaret Goodell (Baylor College of Medicine, Texas, US) and Professor Constanze Bonifer (Institute of Cancer and Genomic Sciences, University of Birmingham, UK). They will tell us about the new findings on the role of epigenetic regulation in normal and malignant hematopoiesis. Dr. Grant Challen (Washington University School of Medicine, St. Louis, US), another expert in this field, will serve as the moderator of the webinar.

2/21/2017
When: 21 February 2017
10am-11:30 am CST
Where: United States
Contact: Heather Nichols
3123215114


Online registration is closed.
« Go to Upcoming Event List  

Hematopoietic stem cells (HSCs) with self-renewal and multi-lineage differentiation capacity are responsible to sustain blood cell production throughout the life-time of an individual. Multiple lines of research have implicated epigenetic regulation has as a central mechanism in establishing and maintaining HSC function. The term epigenetic regulation is used to describe heritable changes in gene expression that do not result from changes in the genome. Epigenetic marks, such as DNA methylation and post-translational histone modifications, create an epigenetic landscape leading to a specific transcriptional program characteristic of each cell type within an organism. In stem cells, this epigenetic landscape is not only responsible to maintain stem cell identity, but also coordinates lineage differentiation towards the different lineages. Furthermore, epigenetic dysregulation has also been established as an important mechanistic driver in several hematological malignancies, where mutations in several epigenetic modifiers are frequently found.

In the last decade, advances in next-generation sequencing have remarkably fueled or understanding on the role of the epigenome in hematopoiesis. In this webinar we will hear from the experts Professor Margaret Goodell (Baylor College of Medicine, Texas, US) and Professor Constanze Bonifer (Institute of Cancer and Genomic Sciences, University of Birmingham, UK). They will tell us about the new findings on the role of  epigenetic regulation in normal and malignant hematopoiesis. Dr. Grant Challen (Washington University School of Medicine, St. Louis, US), another expert in this field, will serve as the moderator of the webinar.  

more Calendar

8/24/2017 » 8/27/2017
ISEH 46th Annual Meeting - Frankfurt, Germany

Association Management Software Powered by YourMembership  ::  Legal