Print Page   |   Contact Us   |   Sign In   |   Become a Member
Site Search
Webinar: HSC bone marrow niche: Is the endosteal or vascular niche the main site for hematopoiesis?
Tell a Friend About This EventTell a Friend
Webinar: HSC bone marrow niche: Is the endosteal or vascular niche the main site for hematopoiesis?

Dr. David Scadden and Dr. Paul Frenette will present opposing views on if the endosteal or vascular niche the main site for hematopoiesis.

9/23/2013
When: 23 September 2013
From 10:00 to 11:00 Central Time
Contact: ISEH Headquarters


Online registration is closed.
« Go to Upcoming Event List  

HSC bone marrow niche: is the endosteal or vascular niche the main site for hematopoiesis?

Sponsored by the ISEH New Investigator Committee



Be part of the New Investigator Committee "Webinar debate”

The Stem Cell Niche Webinar debate: "HSC bone marrow niche: is the endosteal or vascular niche the main site for hematopoiesis?" with David Scadden, Paul Frenette and Andreas Trumpp

Details

Date: 23 September 2013
Time: 10:00 - 11:00 Central Time Convert to your local time here.
Duration
: 1 hour
Moderator: Andreas Trumpp, PhD
Hosts: ISEH - Society for Hematology and Stem Cells

Presenter Information

David Scadden, M.D. - Harvard Stem Cell Institute; Harvard University Department of Stem Cell and Regenerative Biology, Massachusetts General Hospital

Paul Frenette, M.D. - The Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine


Presenters, pictured above left, David Scadden; right, Paul Frenette; below, Andreas Trumpp, moderator

The concept of the stem cell niche was proposed by Schofield in 1978: the stem cell had to be associated with other cells that determine its behaviour to ensure "virtual immortality". Nevertheless, more than 50% of the literature regarding the hematopoietic stem cell niche has been published in the last three years. The stem cell niche field has overcome many challenges including the low frequency of stem cells in the bone marrow and the lack of specific markers on both stem cells and their niche. Through the evolution of many technical improvements, are we getting closer to elucidating the stem cell’s zip code or are we unveiling an underappreciated environmental complexity? From osteoblasts to endothelial cells and reticular cells to megakaryocytes, the list of cellular determinants that maintain stemness is getting larger and more complicated. Do not miss the opportunity to participate in this debate with Dr. David Scadden and Dr. Paul Frenette, two of our prominent ISEH members. Dr. Andreas Trumpp will lead the discussion about different cell types that influence the HSC and whether all niches contribute equally to HSC homeostasis.

ISEH webinars give you the opportunity to engage with our community and be part of this interesting debate.

Association Management Software Powered by YourMembership  ::  Legal