ISEH 2014 New investigators awardees:
1st Place: Albert D. Kim, University of California, San Diego, USA
Notch3 is Required in the Somitic Mircoenvironment for the Specification of Hematopoietic Stem Cells
2nd Place: Jeffrey Bernitz, Ichan School of Medicine at Mount Sinai, USA
Label Retention Selects for Hematopoietic Stem Cells in Aged Bone Marrow and Distinguishes HSCs from Myeloid Restricted Progenitors
3rd place: Jalal Ahmed, Mount Sinai School of Medicine/ MSTP, USA
Dactus Venosus-associated Pericytes form a Niche Regulating Hematopoietic Stem Cell Proliferation in the Fetal Liver
1st place: Daniel D Lipka, German Cancer Research Center (DKFZ), Germany
Whole-genome Bisulfite Sequencing of HSCs and their Immediate Progeny Identifies Novel Regulatory Elements Involved in Self-renewal and Early Hematopoietic Commitment
2nd place: Magali Humbert, IRIC, Canada
LM01/2 Regulates DNA Replication in Hematopoietic Cells
3rd place: Yoshihiro Hayashi, Cincinnati Children's Hospital Medical Center, USA
Modeling and Targeting MLL-PTD/RUNX1 Related MDS/AML in Mouse
Edward Srour, Mervin Yoder, Reuben Kapur and Carlesso Nadia for the publication in Cell Stem Cell of their manuscript " Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent manner." 2014 Jul 3;15(1).
Again to Nadia Carlesso for her paper "Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity." published in Nat Med. 2014 Aug;20(8).
Yuya Kunisaki, Scott Armstrong and Paul Frenette for the publication in Cell Stem Cell of their paper "Acute Myelogenous Leukemia-Induced Sympathetic Neuropathy Promotes Malignancy in an Altered Hematopoietic Stem Cell Niche." 2014 Jul 9. [Epub ahead of print].
Kelli Carroll, Virginei Esain, Mauricio Cortes, Wanda Kwan and Trista North for their paper "Estrogen defines the dorsal-ventral limit of VEGF regulation to specify the location of the hemogenic endothelial niche." published in Dev Cell. 2014 May 27;29(4).
See photos of the award winners at the Annual Meeting below - click here to learn more about the awards