Christa Muller-Sieburg (1952 - 2013)Prof Constanze Bonifer
Christa Muller-Sieburg, a long-standing active member of ISEH, and a pioneer of stem cell research passed away January 2013 in San Diego. She did her PhD with Klaus Rajewski in Cologne, Germany, and then moved to the US to join the lab of Irv Weissman at Stanford University. Here, Christa was the first in the world to prospectively purify hematopoietic stem cells (Muller-Sieburg and Weissman, 1986), a result with a huge impact on basic and medical science. She continued her work in her own lab in La Jolla and studied autonomous regulation and programmed behaviors of adult long-term repopulating HSCs in vivo. In 2002, she and her husband Hans Sieburg demonstrated, for the first time, biased differentiation behavior of individual stem cell clones, again sparking an entire new field of research. Christa's determination, energy and commitment to science was exemplary. She also was a wonderful and generous friend to all whose private lives she touched and an inspiration to her colleagues. Her untimely death in January after a long illness is a huge loss for the stem cell community.
Chair of Experimental Haematology
School of Cancer Sciences
Institute of Biomedical Research
College of Medical and Dental Sciences
University of Birmingham