Xenograft models of human hematopoiesis and leukemia
Dr. Gwenn Danet-Desnoyers will review current xenograft models for the study of: (1) patient-derived acute myeloid leukemia and stem cells, and (2) human hematopoietic stem cells and immune reconstitution. These models play a critical role in the study of the biology of human leukemia and hematopoietic stem cells, and represent animportant tool in translational medicine. Dr. Danet-Desnoyers will highlight their preclinical applications, benefits and challenges. This webinar is targeted to scientist interested in using cutting-edge xenograft models for patient-derived AML, hematopoietic stem cells and human immune reconstitution.
has been the Director of the Stem Cell and Xenograft Core and an adjunct
Associate Professor at the University of Pennsylvania School of Medicine since
2007. His research focuses on human hematopoietic stem cells, acute myeloid
leukemia and xenograft models for the evaluation of therapeutics. Over the past
10 years, he has significantly contributed to the improvement of
patient-derived xenograft models for acute leukemia and the use of
hematopoietic stem cell for human immune reconstitution in immune-deficient
mice. In collaboration with Martin Carroll M.D., he has established one of the
most comprehensive resource laboratories integrating a large tissue bank of
hematologic malignancies with a variety of xenograft models to accelerate pre-clinical
Xenograft models of human hematopoiesis and leukemiaDate: 16 December 2013
Time: 900 - 1000 CST (Convert to your local time here)
Duration: 1 hour
Cost: ISEH Members - Free
non-members - $25.00
Moderator: Martin Carroll, M.D., Medical Director, Stem Cell and Xenograft Core, and Associate Professor of Medicine University of Pennsylvania
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